Chromatografy Flash serii CombiFlash - CombiFlash® Rf 4x

Teledyne ISCO

CombiFlash® Rf 4x

Four-channel, walk-away automation

Multitask like never before with the CombiFlash Rf 4x system, a four-sample automated version of the innovative CombiFlash Rf personal purification system. Its built-in control system acts as an Internet server, generating a web page that can be viewed using a touch screen, desktop or laptop computer running Microsoft® Internet Explorer®. You and your colleagues can monitor progress and schedule your time more productively.

The CombiFlash Rf 4x system uses precision-packed RediSep® Rf columns from 4 grams to 330 grams, which are quickly interchangeable with no additional hardware — saving you time and money. You can also use multiple column sizes and various stationary phases in one batch. Enjoy fast, easy scale-up from milligrams to tens of grams of purified sample.

Standard Features

  • Sense remaining solvent volume in supply bottles with optional solvent management module.
  • Multi-sample automation lets you share resources with other chemists, without waiting in line.
  • Different size columns (4 grams to 330 grams) can be used for each channel.
  • RFID column sensing automatically programs optimal parameters for each sample channel; channels can also run with customized parameters.
  • Up to 200 psi operating pressure – ideal for reversed phase Flash chromatography.
  • Delivers four times the productivity in less than nine inches of linear bench space.
  • Increase work efficiency with multiple columns – load and program new runs without interrupting the purification in progress.
  • Sample automation lets you share resources with other chemists, without waiting in line.
  • An optional post-run air purge can clear solvent from all columns before disposal.
  • Automatic, self-cleaning valve allows unattended operation and minimizes cross-contamination.
  • The system can deliver waste fluids from each channel to independent containers and can monitor the fluid level in each to prevent over-filling.
  • Convert from normal to reversed phase conditions in minutes.


  • Drug discovery
  • Agrochemistry
  • Petrochemistry
  • Quick scale up of intermediate compounds from milligram to several grams

Options and Accessories

  • RediSep Rf prepacked columns
  • Sample load prepacked cartridges
  • Sample load, empty cartridges